D. Questionnaires/letters
D.1. AN EXAMPLE OF A SUITABLE LETTER FOR THE PATIENT TO TAKE TO THE ALLGERGY CONSULTATION
Dear colleague,
(Insert patient's name and details) had a hypersensitivity reaction after the administration of a contrast agent on (insert date).
Examination type (e.g. CT, MRI, IV.....):
Type of contrast agent:
- iodine-based
- gadolinium-based
- ultrasound
Name of the contrast agent:
Dose administered: ml
Route of administration (e.g. IV, IA, intra-articular, oral, local......):
Time between the injection and the start of the clinical symptoms:
Type of symptoms (describe):
Grade of the reaction according to the Ring and Messmer classification:
- Grade 1
- Grade 2
- Grade 3
- Grade 4
| Grade | Dermal | Abdominal | Respiratory | Cardiovascular |
| 1 |
Pruritus Flushing Urticaria Angioedema |
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| 2 |
Pruritus Flushing Urticaria Angioedema |
Nausea Cramping
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Rhinorrhea Hoarseness Dyspnea
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Tachycardia (> 20 bpm) Blood pressure change (> 20 mm Hg systolic) Arrhythmia
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| 3 |
Pruritus Flushing Urticaria Angioedema |
Vomiting Defecation Diarrhea
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Laryngeal edema Bronchospasm Cyanosis
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Shock
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| 4 |
Pruritus Flushing Urticaria Angioedema |
Vomiting Defecation Diarrhea
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Respiratory arrest
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Carciac arrest
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Treatment given during the reaction:
- (please specify)
Outcome (e.g. follow up, ICU, return home ......):
Histamine and/or Tryptase blood tests:
Blood test performed at the time of the reaction Yes/No
2 hours later Yes/No
Results: Histamine:
Tryptase:
Previous history of contrast agent reaction Yes/No
If yes, please specify type of contrast agent and symptoms
Thank you for seeing the patient and performing skin testing to categorize the reaction as either allergic or non-allergic hypersensitivity, and to look for cross-reactivity so that a safer contrast agent can be recommended for future injections.
Your sincerely,
Dr (Name and details)
D.2. QUESTIONNAIRE FOR IODINE-BASED CONTRAST MEDIA ADMINISTRATION TO BE COMPLETED BY THE REFERRING CLINICIAN
| Questionnaire for iodine-based contrast media administration to be completed by the referring clinician | |||
| Yes | No | ||
| 1. | History of moderate or severe reaction to an iodine-based contrast medium | |
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| 2. | History of atopy requiring treatment | ![]() |
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| 3. | History of unstable asthma | ![]() |
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| 4. | Hyperthyroidism | ![]() |
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| 5. | Heart failure | ![]() |
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| 6. | Diabetes mellitus | ![]() |
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| 7. | History of renal disease | ![]() |
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| 8. | Previous renal surgery | ![]() |
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| 9. | History of proteinuria | ![]() |
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| 10. | Hypertension | ![]() |
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| 11. | Gout | ![]() |
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| 12. |
Most recent measurement of serum creatinine • Value............................................. |
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| 13. |
Is the patient currently taking any of the following drugs |
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Completed by ______________________________________ Date ________________________
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D.3. QUESTIONNAIRE FOR GADOLINIUM-BASED CONTRAST AGENT ADMINISTRATION TO BE COMPLETED BY THE REFERRING CLINICIAN
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Questionnaire for gadolinium-based contrast agent administration to be completed by the referring clinician |
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| Yes | No | ||
| 1. | History of moderate or severe reaction to a gadolinium-based contrast medium | |
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| 2. | History of atopy requiring treatment | ![]() |
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| 3. | History of unstable asthma | ![]() |
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| 4. | Has the patient end-stage renal failure (eGFR < 30 ml/min/1.73m2) or is the patient on dialysis | ![]() |
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| 5. | Has the patient reduced renal function* (eGFR between 30 and 60 ml/min/1.73 m2) | |
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* Only if high-risk agents are used
Completed by ______________________________________ Date ________________________
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D. Questionnaires